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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Relation of endemic dental fluorosis to malnutrition

February 1952 | Journal of the American Dental Association | Massler M, Schour I. | 44:156-165.
The data from this and other investigations suggest that malnourished infants and children, especially if deficient in calcium intake, may suffer from the effects of water containing fluorine while healthy children would remain unaffected. . . . Thus low levels of fluoride ingestion which are generally considered to be safe for the general population may not be safe for malnourished infants and children. Therefore, the nutritional status must be carefully assessed and guarded in areas with endem

Fluorides and Osteoporosis

February 25, 1967 | The Lancet | Meema HE. | 289(7487):444.
SIR, - In your annotation (Jan 28, p. 203) the preventive action of fluorides on osteoporosis is said to be confirmed by the recent findings of Bernstein et al. While it is quite possible that fluorides may have such an effect, the cited article has several deficiencies which in my opinion are severe enough to cast doubt on the validity of the results. Of the factors known to influence the development and severity of involutional osteoporosis, age is of prime importance. In the paper under scru

Summary of workshop on drinking water fluoride influence on hip fracture on bone health. (National Institutes of Health, 10 April, 1991)

May 1992 | Osteoporosis International | Gordon SL, Corbin SB. | 2(3):109-17.
An ecologic study [22] compared fracture rates in 216 counties with natural fluoride levels greater than 0.7 ppm with rates in 95 counties with naturally low fluoride (less than 0.4 PPM) in the drinking water (Dose Ecology Study). Hip fracture ratios used as a denominator the hip fracture rates in low fluoride areas. Medicare data obtained from the Health Care Financing Administration, DHHS, was used to obtain hospitalization rates for upper femur and lower spine fractures in men and women over

Water fluoridation and hip fracture

July 24-31, 1991 | Journal of the American Medical Association | Cooper C, Wickham CA, Barker DJ, Jacobsen SJ. | 266(4):513-4.
In a recent article in THE JOURNAL, Jacobsen et al (1) demonstrated a positive ecologic association between hip fracture discharge rates in the United States and fluoride content in water supplies. In a similar study, we recently reported the ecological association of discharge rates for hip fracture and water fluoride levels in 39 county districts in England. (2) Our study was performed in response to the suggestion that fluoridation of water might serve to stem the rising tide of hip fracture