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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Role of renal function in the association of drinking water fluoride and plasma fluoride among adolescents in the United States: NHANES, 2013–2016.

June 7, 2022 | Environmental Research | Danziger J, Dodge LE, Hu H. | [Epub ahead of print]
Introduction Fluoride enrichment of drinking water is one of the major public health advances of the 21st century. While fluoride toxicity has been reported with acute intoxication (Gessner et al., 1994; Penman et al., 1997), emerging data suggests that even low levels of exposure may be associated with adverse effects in vulnerable populations (Wei et al., 2021a; Yasmin and Ranjan, 2015; Riddell et al., 2019; Green et al., 2019). While there are known determinants of fluoride toxicity, i

High Fluoride Ingestion Impairs Bone Fracture Healing by Attenuating M2 Macrophage Differentiation.

May 20, 2022 | Frontiers in Bioengineering and Biotechnology | Du C, Xiao P, Gao S, Chen S, Chen B, Huang W, Zhao C. |
Introduction Long-term and excess fluoride consumption induces disturbed homeostasis of the bone and a series of chronic systemic diseases (Erdal and Buchanan, 2005). The World Health Organization has stated that the maximum safe limit of fluoride in drinking water is 1.5 ppm; however, more than 50 countries have high fluoride levels in drinking water (Rango et al., 2012; Perumal et al., 2013; Yu et al., 2018; Zhou et al., 2019). Fluorosis is endemic in at least 25 countries around the world, o