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Association between fluoride, magnesium, aluminum and bone quality in renal osteodystrophy

In conclusion, trace elements such as fluoride, magnesium, and aluminum have an effect on bone in renal failure patients. These trace elements affect the different types of ROD differently, influencing bone through different modes of action. Fluoride interfered with bone mineralization and increased osteoid content, which was most evident in osteomalacia and the mixed bone disorder. In addition, fluoride may interact with aluminum to worsen the osteomalacic lesion. Magnesium appeared to affect b