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Effectiveness of school-based strategies to prevent tooth decay in Filipino children: A cluster-randomized trial.

Objectives Evidence for affordable and pragmatic programmes to address the burden of untreated tooth decay in children in low- and middle-income settings is limited. This study aimed to (1) assess the effect of a government-run, school-based daily group toothbrushing programme compared to standard school-based oral health education on the incidence of dental caries and odontogenic infections in Filipino children over a period of 3 years; and (2) assess the additional preventive e

Effects of long-term fluoride exposure are associated with oxidative biochemistry impairment and global proteomic modulation, but not genotoxicity, in parotid glands of mice.

Background Fluoride has become widely used in dentistry because of its effectiveness in caries control. However, evidence indicates that excessive intake interferes with the metabolic processes of different tissues. Thus, this study aimed to investigate the effects of long-term exposure to F on the parotid salivary gland of mice, from the analysis of oxidative, proteomic and genotoxic parameters. Materials and methods The animals received deionized water containing 0, 10 or 50

The effect of community water fluoridation cessation on children’s dental health: a national experience.

Background Community water fluoride (CWF) is the proven cornerstone of primary dental health care promotion. In 2002 CWF was made mandatory at a national level in Israel, however a new government revoked these regulations in August 2014. "Maccabi" is the second largest national health care provider with 2.3 million members, "Maccabi-Dent", its dental branch, has 53 clinics, employing 1100 dentists. The aim of this study was to evaluate the cumulative effect on treatment rates 6 years aft

Sex-specific effects of fluoride and lead exposures on histology, antioxidant physiology, and immune system in the liver of zebrafish (Danio rerio).

Affiliations College of Veterinary Medicine, Shanxi Agricultural University, Taigu, 030801, Shanxi, China Guodong Wang, Tianyu Wang, Xiulin Zhang & Jianjie Chen College of Biological and Food Engineering, Anyang Institute of Technology, Anyang, 455000, Henan, China Guodong Wang College of Food Science and Technology, Shanxi Agricultural University, Taigu, 030801, Shanxi, China Cuiping Feng, Shaojun Yun, Yanfen Cheng, Feier Cheng & Jinling Cao Correspon

Grading and quantification of dental fluorosis in zebrafish larva.

Section snippets Zebrafish culture and fluoride treatment The adult AB zebrafish were maintained at the zebrafish facility at 28 °C with a cycle of 14 h light and 10 h dark, and they were feed with brine shrimp three times a day. One male and one female zebrafish were paired for the spawning. All the animal experiment protocols were approved by IRB of School of Stomatology, the Fourth Military Medical University. Once the zebrafish eggs were laid, they were cultured in the embryo me