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Allergy to fluoride

The literature contains little information concerning allergic reactions to the fluorine ion. Indeed some have-questioned the possibility that fluoride in such a small amount as is present in vitamin tablets, toothpastes or water could act as a sensitizer. Two other halogens, iodine and bromine are recognized as sources of allergic manifestations. Feltman and Kosel [1] noted atopic dermatitis, urticaria, epigastric distress, emesis, and headache in one per cent of 672 pregnant women and child