Effects of dialysate calcium and fluoride on bone disease during regular hemodialysis
February 1972
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Journal of laboratory and clinical medicine
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Jowsey J, Johnson WJ, Taves DR, Kelly PJ.
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79(2):204-14.
Increased osteoid is typically found in fluorosis, hence, ascribing our findings to an F effect seems reasonable. There are several possible reasons for F causing increased osteoid. In vivo, excessive F can result in increased bone production and failure of mineralization… It may be noteworthy that 4 of the 5 patients with the most disabling symptoms of bone pain, muscle weakness, wasting and multiple spontaneous fractures were exposed to high-F dialysate. This would suggest that prolonged exp