-

On fluoride and bone strength

We welcome the opportunity to respond to the letter by Baylink et al. Their letter makes many good points but, unfortunately, it also contains several misinterpretations of our analysis. The thesis of Baylink's letter and the paper of Einhorn et al. [1] is that fluoride incorporation into cortical bone does not impair the bone's mechanical properties. We assert that the apparent effect of fluoride on bone strength depends on how strength is defined [2, 3]. It is important to recognize the differ

On fluoride and bone strength

The recent paper by Einhorn et al. [1] drew the conclusion that fluoride incorporation into bone does not impair bone's mechanical properties. This result is in conflict with the results of others concerning fluoride and bone strength. For instance, several investigators--including ourselves--have shown that bone strength decreases as bone fluoride levels in the mineral phase increase to beyond about 4500 ppm [2-7]. When the fluoride content in the mineral phase reaches 10,000 ppm, bone strength