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The effect of fluoride treatment on bone mineral in rabbits

“In this study, despite the observed increased in hardness of both cancellous and cortical bone, the fracture stress and elastic modulus of vertebrae tested in compression and femora tested in three-point bending were decreased by fluoride treatment. The fact that the hardness (which is dependent largely on the mineral content) increases even though the modulus (which depends on both the mineral content and the collagen) decreases suggests that there is a change in the relationship between the