-

Estimation of occupational hazards of the employees of a phosphate fertilizers plant.

In our research no essential changes in blood morphology and kidneys function were found, as well as estimation of liver efficiency was positive. The biggest number of changes which indicate toxic effect of fluorine, was found while analysing sugar curves and phosphorus-calcium-magnesium balance. Six cases of diabetes, 4 of them of early type were diagnosed, mainly in production division. On an average, the biggest levels of sugar unfed as well as after administering of glucose, were found at

Fluorosis–a rare complication of diabetes insipidus.

The familial pituitary or central diabetes insipidus (DI) is a relatively rare condition with variable onset, from birth to several years of age and variable severity within a family and in individuals over time(l). Severe dehydration and growth retardation, though rare are known compilations of DI. However, dental fluorosis as a complication of DI has been described in the literature only in three families(2,3). Further, severe crippling deformities due to skeletal fluorosis has not been report

Red blood cell glucose metabolism in human chronic fluoride toxicity

Fluoride is a well known inhibitor of many enzyme systems in vitro (Shahed etal. 1979; Messer 1984). The most widely studied classic example of fluoride inhibition is its potent inhibition of glycolysis, specifically its action on the enzyme enolase (Warburg and Christian 1941; Shearer and Suttie 1970; Repaske and Suttie 1979; Shahed et al. 1979). Despite the plethora of in vitro studies on the effects of fluoride on the enzyme activity, there is a paucity of information concerning the in vivo m