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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Endemic fluorosis in Turkish patients: relationship with knee osteoarthritis

September 2001 | Rheumatology International | Savas S, Cetin M, Akdogan M, Heybeli N. | 21(1):30-5.
Endemic fluorosis may increase the severity of osteoarthritis in the knees. . . . Twelve patients (21.4%) with endemic fluorosis and eight control patients (20%) had grade 2 osteoarthritis, 16 patients (28.6%) with endemic fluorosis and three control patients (7.5%) had grade 3 osteoarthritis, and six patients (10.7%) with endemic fluorosis and one control patient (2.5%) had grade 4 osteoarthritis. The osteoarthritis severity was greater in the endemic fluorosis group. Osteophytes at the anterio

Brick tea fluoride as a main source of adult fluorosis

April 2003 | Food and Chemical Toxicology | Cao J, Zhao Y, Liu J, Xirao R, Danzeng S, Daji D, Yan Y. | 41(4):535-42.
[A]rthopathy and arthritis affected a significant number of the (fluorosis) patients, resulting in functional disability. . . . The physical signs of brick-tea type skeletal fluorosis were elbow, shoulder and knee articular dysfunction, which was the most common pathology. X-ray examination revealed that the interosseous membrane ossification, tendon attachment calcification and articular degeneration were the causes of these functional disorders.

Spinal cord compression revealing fluorosis

January 2008 | Joint, Bone, Spine | Hafsa C, Zaghouani H, Kriaa S, Salem R, Omezzine SJ, Golli M, Touzi M, Berguaoui N, Gannouni A. | 75(1):91-3.
1. Introduction Bone fluorosis due to high fluoride contents in water and soil is endemic in North Africa and India. Neurological complications are rare. They consist of nerve root or spinal cord compression by bony excrescences, which predominate at the cervical spine. We report a new case of spinal cord compression due to ossification of the posterior vertebral ligament in a patient with bone fluorosis. 2. Case-report This 49-year-old woman from southern Tunisia experienced increased diffic

Ossification of the posterior longitudinal ligament and fluorosis

May 1992 | Journal of Bone and Joint Surgery | Rao BS, Taraknath VR, Sista VN. | 74-B(3):469-70.
There is only one report of ossification of the posterior longitudinal ligament (OPLL) in patients suffering from fluorosis. Deshpande, Dinakarand Reddy (1976) mention an association with fluorosis in 14 of 26 cases. OPLL is not mentioned in two reviews of fluorosis (Jolly 1981; Reddy and Reddy 1987). Patients. In our neurological service, we saw 15 cases of OPLL in one year, allpresenting with spinal compression. They accounted for about 1 .5% of all spinal cases. Ten of them had associated