Study Tracker

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Altered sperm chromatin structure in mice exposed to sodium fluoride through drinking water

June 2012 | Environmental Toxicology | Sun Z, Niu R, Wang B, Wang J. | 29(6):690-6.

No relationship between subchronic fluoride intake and DNA damage in Wistar rats.

November-December 2004 | Caries Research | Ribeiro DA, Marques ME, de Assis GF, Anzai A, Poleti ML, Salvadori DM. | 38(6):576-9.

Absence of DNA damage in multiple organs (blood, liver, kidney, thyroid gland and urinary bladder) after acute fluoride exposure in rats

May 2007 | Human & Experimental Toxicology | Leite Ade L, Santiago JF Jr, Levy FM, Maria AG, Fernandes Mda S, Salvadori DM, Ribeiro DA, Buzalaf MA. | 26(5):435-40.

Leukocyte response in young mice chronically exposed to fluoride

July 1982 | Fluoride | Greenberg SR. | 15(3):119-123

Genotoxic damage in oral epithelial cells induced by fluoride in drinking-water on students of Tula de Allende, Hidalgo, Mexico

October 2012 | Journal of Toxicology and Environmental Health Sciences | Vazquez-Alvarado P, Melendez-Ocampo A, Ortiz-Espinosa RM, Munoz-Juarez S, Hernandez-Ceruelos A. | 4(8):123-129

DNA damage, apoptosis and cell cycle changes induced by fluoride in rat oral mucosal cells and hepatocytes

February 21, 2006 | World Journal of Gastroenterology | He LF, Chen JG. | 12(7):1144-8.

Genotoxic evaluation of sodium fluoride and sodium perborate in mouse bone marrow cells

March 2005 | Bulletin of Environmental Contamination and Toxicology | Velazquez-Guadarrama N, Madrigal-Bujaidar E, Molina D, Chamorro G. | 74(3):566-72.

The LD50 was obtained as the geometric mean of the determined experimental data on mice lethality. The value for sodium fluoride was 32 mg/kg and for sodium perborate the result was 775 mg/kg. The results concerning the SCE rate induced by sodium fluoride are shown in Table 1. Although no significant increase was observed with the two low doses tested (from 2 to 4 mg/kg), a significant SCE increase was found with the three highest doses. The cumulative frequency of these data reveals about 70% o

Research Studies

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.

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