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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Skeletal fluorosis mimicking seronegative arthritis

March-April 2007 | Scandinavian Journal of Rheumatology | Gupta R, Kumar AN, Bandhu S, Gupta S. | 36(2):154-5.
Fluorosis is endemic in certain parts of the world, especially the Asian subcontinent (1). We report an unusual presentation of fluorosis mimicking seronegative spondyloarthritis. Although fluorosis is known to cause irritable bowel syndrome-like disorder and joint pain, this could be wrongly diagnosed as a case of seronegative arthritis. Case report A 35-year-old female presented with joint pain involving the lower back, both heels, and the knee for the past 3 years. She described early m

Mottled enamel in Oklahoma Panhandle, and its possible relations to child development

September 1938 | Journal of the Oklahoma State Medical Association | Blue JA. | 31(9):295-301.
Summary and Conclusions 1. Results of surveys made in Oklahoma Panhandle on Chronic Fluorine Intoxication was stated, the endemic areas located, the mottled enamel index derived, the fluorine content of the water supply of the different areas given along with the depth of the wells, along with the findings on physical examinations of those afflicted with this condition. 2. That there is evidence which indicates that there is a definite relation between chronic fluorine poisoning as detected by

Multiple painless masses: periostitis deformans secondary to fluoride intoxication

April 2014 | Skeletal Radiology | Chitkara M, Rackoff PJ, Beltran LS. | 43(4):529-30, 555-6.
Diagnosis The differential diagnosis based on the imaging findings included ossification of subperiosteal hematomas, ectopic calcification in the setting of a connective tissue disorder, and periostitis deformans secondary to fluoride intoxication. Laboratory assays were requested by the patient’s rheumatologist, which were notable for a mildly elevated alkaline phosphatase level (216 U/L, reference range=40–115 U/L) and a markedly elevated serum fluoride level (3.9 mg/L, normal range <

Skeletal fluorosis and instant tea

January 2005 | The American Journal of Medicine | Whyte MP, Essmyer K, Gannon FH, Reinus WR. | 118(1):78-82.
Tea drinking remains popular in the United States and increasingly is suggested to promote health. We caution that skeletal fluorosis can result from consumption of excessive amounts of instant tea because of substantial fluoride levels in some commercial preparations. Case report A 52-year-old white woman consulted in 1998 for dense lumbar vertebras discovered after twisting her back. Spinal discomfort and stiffness for 5 years reflected “disc disease.” She had never had a fracture. Chest