Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Cytogenetic effect of inorganic fluorine compounds on human and animal cells in vivo and in vitro

1973 | Genetika | Voroshilin SI, Plotko EG, Gatiyatullina EZ, Giliova EA. | 9(4):115-20.
On the grounds of the results obtained during our experiments F compounds are able to produce certain changes in chromosomes from somatic cells of animals treated in vivo by them… Most of the aberrations observed in the case of bone marrow cells were chromatid-type aberrations… [W]e entertain the opinion that the main damage to chromosomes during our experiments with F compounds also took part during the S-phase… [T]hese data enable us to consider as sufficiently established the conclusion

Micronucleus and sister chromatid exchange frequency in endemic fluorosis

August 1995 | Fluoride | Wu DQ, Wu Y. | 28(3):125-127.
Introduction Although widespread in occurrence, fluorine (as fluoride ion, F-) does not have any known physiological requirement. It is generally accepted, however, that long term over-intake of fluoride may cause skeletal as well as dental fluorosis. Many studies on other toxic effects of fluoride have been made, including whether it alters human genetic material and ultimately leads to more serious harm. (1) At present, various test systems and methods have been developed to detect fluoride