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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Characterization of nervous system intoxication in occupational fluorosis

May 1974 | Gigiena Truda i Professional’nye Zabolevaniia | Popov LI, Filatova RI, Shersheyer AS. | (5):25-27.
Fluorine is a poison with a broad spectrum of action affecting the metabolic processes, tissue respiration, and neuroendocrine regulation. For this reason, even before affecting the bones, occupational fluorosis manifests itself clinically as a generalized disease with syndromes affecting a number of important systems and organs, including the nervous system. The neurotoxic effect of fluorine compounds has been proven by numerous experimental studies (A. F. Aksyuk and G. V. Bulychev; S. K. Bi

Analyses of ECGs in 271 cases with dental fluorosis

1988 | Chinese Journal of Endemiology | Zhou O, Zhang D. | 5(4):296-97.
Our team performed investigations in Yuqing Village and Guanfang Village (1) which were seriously affected by endemic fluorosis, from September to October 1985; those two villages are only 1,500 meters distant from Mangbu District of Zhenxiong County, and the life and production conditions in these two villages are similar to those in Mangbu District, only that these two villages are heavily polluted by coal smoke from daily use. We performed a total of 292 electrocardiograms (ECGs) on villagers

The effect of small quantities of fluorine on the human body

1962 | Gigiena i Sanitariia | Aksyuk AF, Bulichev GV, Erisman FF. | 27:7-10.
Based on several studies, national standard GOST 2874-54 established the maximum allowable concentration of fluorine in drinking water to be 1.5 mg/l. However, this standard cannot be considered sufficiently substantiated. Despite the fact that fluorine exhibits strong neurotropic activity, the question pertaining to the functional state of the nervous system as a result of the long-term intake of fluorine in the drinking water has remained open. Moreover, several indications of endemic fluorosi