Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Time trends for bone and joint cancers and osteosarcomas in the Surveillance, Epidemiology and End Results (SEER) Program

1991 | Public Health Service; Review of Fluoride: Risks and Benefits | Hoover RN, Devesa S, Cantor K, Fraumeni JF. | Appendix F; p. F1-F7
At the request of the Committee, we have enclosed a brief description of the time trends for bone and joint cancers and for osteosarcomas in the Surveillance, Epidemiology and End Results (SEER) Program of the National Cancer Institute (NCI), and the relationship of these trends to fluoridation of drinking water supplies. The SEER Program, begun in 1973, is a group of population-based cancer registries that covers approximately 10% of the U.S. population. In contrast to our main report which foc

Age-specific fluoride exposure in drinking water and osteosarcoma (United States).

May 2006 | Cancer Causes & Control | Bassin EB, Wypij D, Davis RB, Mittleman MA. | 17(4):421-8.
Funders who supported this work: NIDCR NIH, HHS (1) References  Articles referenced by this article (43) Link MP, Eilber F (1997) Osteosarcoma. In: Pizzo PA, Poplack DG (eds) Principles and practice of oediatric oncology, 3rd edn. Lippincott-Raven Co., Philadelphia, pp 889–920 Bone cancers. Dorfman HD, Czerniak B. Cancer, (1 Suppl):203-210 1995. MED: 8000997 Incidence and survival rates of children and young adults with osteogenic

Distribution of fluoride to human breast milk following intake of high doses of fluoride.

1984 | Caries Research | Ekstrand J, Spak CJ, Falch J, Afseth J, Ulvestad H. | 18(1):93-5.
Excerpt The present study demonstrates that, in spite of the high fluoride dose administered to the mother (11.25 mg), the child receives a maximum dose of 30 ug fluoride/day, or 0.2% of the dose given to the mother. This is only 3% of the dose compared with the daily fluoride dose to bottle-fed children. With a baby formula diluted with 1 ppm fluoride water, bottle-fed children receive approximately 1 mg/day. In conclusion, this study shows that there is a slight increase in the fluoride co

No evidence of transfer of fluoride from plasma to breast milk.

September 19, 1981 | British Medical Journal | Ekstrand J, Boreus LO, Chateau P. | 283: 761-2.
Artificially fluoridated drinking water is supplied throughout the world as a mass-prophylactic against dental caries. No data are available, however, on the transfer of fluoride from maternal plasma to breast milk. We have therefore compared the fluoride concentration in the plasma and breast milk of nursing mothers after an oral dose of fluoride. Subjects and Methods Five mothers aged 27-36 years were given fluoride by mouth on the third postpartum day. A dose of 1.5 mg was given as an a