As a strong oxidant, fluorine can induce oxidative stress resulting in cellular damage. Ferroptosis is an iron-dependent type of cell death caused by unrestricted lipid peroxidation (LPO) and subsequent plasma membrane rupture. This article indicated a relationship between fluorosis and ferroptosis. Evidence of the depletion of glutathione (GSH) and increased oxidized GSH can be found in a variety of organisms in high fluorine environments. Studies have shown that high fluoride levels can re
Abstract
This review focuses on the synthesis of current experimental and observational data regarding the effect of fluoride exposure on childhood mental health and the role of mitochondrial function as a mechanism of action. We aggregated data on the relationships between fluoride neurotoxicity, mitochondrial function, and cognitive and mental health using PubMed. Current animal and human research suggest that prenatal and perinatal fluoride exposure might have
Abstract
Objective
This research aims to know the influence of fluoride in drinking water towards Fluorosis and the Intelligence Level of Elementary School Students in Palu City.
Method
This cross-sectional study was performed through descriptive analysis on 100 students aged 6–12 years old selected by stratified random sampling from two different areas with different levels of fluoride in drinking water in Palu City. The samples were collected from two different elementary sch
Abstract
Background
Dental fluorosis is caused by prolonged exposure to excessive fluoride during the period of permanent tooth formation and is characterized by tooth discoloration, pitting, and loss of shape. Communities living near Lake Kivu in Western Rwanda exhibit a high prevalence of dental fluorosis; however, data on prevalence and risk factors are scarce.
Methods
This cross sectional, quantitative study used a One Health approach to investigate dental fluorosis prevalence amon
For decades, fluoride has been the pre-eminent ingredient in consumer products to prevent dental caries. The evidence that fluoridated toothpaste significantly reduces caries is well documented. 8 , 9 It is now widely accepted that fluoride prevents dental decay by encouraging topical remineralization of early white spot, incipient lesions. New non-fluoride remineralization strategies have emerged that seem to be promising. 10
The primary concern with fluoridated toothpastes used by c
Abstract
Objectives:
This investigation aimed to determine whether fluoride concentration in water at the user endpoint remains the same as at the adjusted source, i.e., water treatment facilities.
Methods
Daycares in Alberta, Canada, were used as the endpoint to measure fluoride concentration. They were randomly selected from a list of 400 licensed daycares provided by the Ministry of Children’s Services. All water samples collected from the daycares were sent to the accredited Alberta
Abstract
Fluoride exposure is associated with later pubertal development and decreased testosterone production in adolescent and adult males. However, its effects on female reproductive health and pubertal development are unclear. Therefore, we examined associations of fluoride exposure with reproductive health outcomes among adolescent girls and women in the United States. Participants were from The National Health and Nutrition Examination Surveys (2013 to 2016), aged 16–19 and iden
