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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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On fluoride and bone strength

1993 | Calcified Tissue International | Turner CH, Dunipace AJ. | 53:289-90.
The recent paper by Einhorn et al. [1] drew the conclusion that fluoride incorporation into bone does not impair bone's mechanical properties. This result is in conflict with the results of others concerning fluoride and bone strength. For instance, several investigators--including ourselves--have shown that bone strength decreases as bone fluoride levels in the mineral phase increase to beyond about 4500 ppm [2-7]. When the fluoride content in the mineral phase reaches 10,000 ppm, bone strength

The effect of 0.05 percent dietary sodium fluoride on the rat kidney

1957 | Acta Pharmacologica et Toxicologica | Pindborg JJ. | 13(1):36-45.
Two hundred and twenty-six white rats were given a diet containing 0.05 per cent sodium fluoride (226 ppm) for periods ranging from 3 to 56 days. It was established that changes in the kidneys occurred regularly after 21-28 days on the diet. The kidney changes consisted primarily in dilatation of the Henle loops in the juxtacortical area of the medulla, soon followed by a flattening of the epithelium in the convoluted tubules in the cortex and a distention of the tubules, possibly due to some k