Study Tracker

Pathological changes in the tissues of rats (albino) and monkeys (macaca radiata) in fluorine toxicosis

1953 | Journal of the Indian Institute of Science | Wadhwani TK, Ramaswamy AS. | 35(3):223-30.

From the photo-micrographs given here, it can be seen that fluorine seems to cause a selective destruction of the epithelium. The epithelium has been found to be considerably damaged in the stomach, duodenum, small intestine, lungs and thyroid. The loss or damage of the epithelium of the digestive tract would undoubtedly have an adverse effect on the functions of the tract. Such a circumstance has rather already been demonstrated (Wadhwani, 1953). It has been shown that, as a result of F ingesti

Chronic administration of aluminum-fluoride or sodium-fluoride to rats in drinking water: alterations in neuronal and cerebrovascular integrity

February 16, 1998 | Brain Research | Varner JA, Jensen KF, Horvath W, Isaacson RL. | 784(1-2):284-98.

“While the small amount of AlF in the drinking water of rats required for neurotoxic effects is surprising, perhaps even more surprising are the neurotoxic results of NaF at the dose given in the present study [1.0 ppm F]... The results of the present study indicate that more intensive neuropathological evaluations of F effects on brain may prove to be of value... In summary, chronic administration of AlF and NaF in the drinking water of rats resulted in distinct morphological alterations in t

Chronic aluminum fluoride administration. I. Behavioral observations

May 1994 | Behavioral and Neural Biology | Varner JA, Horvath WJ, Huie CW, Naslund HR, Isaacson RL. | 61(3):233-41.

Chronic AIF3 Administration: II. Selected Historical Observations.

1993 | Neuroscience Research Communications | Varner JA, Huie C, Horvath W, Jensen KF, Isaacson RL. | 13(2):99-104.

Changes in fluoride levels in the liver, kidney, and brain and in neurotransmitters of mice after subacute administration of fluoride

November 2005 | Fluoride | Tsunoda M, Aizawa Y, Nakano K, Liu Y, Horiuchi T, Itai K, Tsunodaf H. | 38(4):284-292.

Histological changes in the brain of young fluoride-intoxicated rats

2002 | Fluoride | Shivarajashankara YM, Shivarajashankara AR, Bhat PG, Rao SM, Rao SH. | 35(1):12-21.

Decreased nicotinic receptors in PC12 cells and rat brains influenced by fluoride toxicity–a mechanism relating to a damage at the level in post-transcription of the receptor genes

August 5, 2004 | Toxicology | Shan KR, Qi XL, Long YG, Nordberg A, Guan ZZ. | 200(2-3):169-77.

Fluoride-induced depletion of polyphosphoinositides in rat brain cortical slices: a rationale for the inhibitory effects on phospholipase C

July 1999 | International Journal of Developmental Neuroscience | Sarri E, Claro E. | 17(4):357-67.

Ameliorative effects of oleanolic acid on fluoride induced metabolic and oxidative dysfunctions in rat brain: experimental and biochemical studies

April 2014 | Food and Chemical Toxicology | Sarkar C, Pal S, Das N, Dinda B. | 66:224–236.

New data for the validation of the mean daily maximum permissible concentration of hydrogen fluoride in atmospheric air

1968 | American Institute of Crop Ecology Survey of USSR Air Pollution Literature: A Second Compilation of Technical Reports on the Biological Effects and Public Health Aspects of Atmospheric Pollutants (1972, Nuttonson, ed.) | Sadilova MS, Plotko EG, Yel | p.24-32.