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Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Genotoxic evaluation of sodium fluoride and sodium perborate in mouse bone marrow cells

March 2005 | Bulletin of Environmental Contamination and Toxicology | Velazquez-Guadarrama N, Madrigal-Bujaidar E, Molina D, Chamorro G. | 74(3):566-72.
The LD50 was obtained as the geometric mean of the determined experimental data on mice lethality. The value for sodium fluoride was 32 mg/kg and for sodium perborate the result was 775 mg/kg. The results concerning the SCE rate induced by sodium fluoride are shown in Table 1. Although no significant increase was observed with the two low doses tested (from 2 to 4 mg/kg), a significant SCE increase was found with the three highest doses. The cumulative frequency of these data reveals about 70% o