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Aggravation of dermatitis herpetiformis by dental fluoride treatments

It has been well established that ingestion of iodides or the painting of the pharynx with iodine will exacerbate dermatitis herpetiformis [1]; it is not well recognized that fluorides may do so. I report a patient with dermatitis herpetifonnis whose disease was apparently aggravated by application of fluoride to his teeth. Case report. An 83-year-old man had had the onset of typical dermatitis herpetiformis at the age of 75. The disease had been satisfactorily controlled for several years by a

Effects of fluoride on bone in Finland. Histomorphometry of cadaver bone from low and high fluoride areas

The main histolological change induced by fluoride is the increase of osteoid volume… This increase in osteoid parameters was observed in our study already at fluoride concentrations above 1.5 ppm. . . .  Fluoridation of drinking water up to 1.2 ppm apparently does not pose a potential risk to bone provided the renal function is normal. . . . We should, however, recognize that it is difficult to give a strict value for a safe fluoride concentration in drinking water, because individual suscep

Reproductive toxicity of fluoride

Perfluorochemicals are compounds in which all the hydrogen atoms have been replaced by fluorine atoms. Because of their high capacity to dissolve oxygen, perfluorochemicals have been used as artificial oxygen carriers in organ perfusions. Previous experiments suggested that perfluorochemicals failed to support testosterone secretion by rat testes. We hypothesized that fluoride ions in the perfusion medium may have been the toxic factor. We tested this hypothesis by adding sodium fluoride to perf