Study Tracker

Effects of chronic fluorosis on CAMKIIA, C-FOS, BAX, and BCL-2 channel signalling in the hippocampus of rats

July-September 2013 | Fluoride | Zhang J, Zhang Z | 46(3)135–141

The analog of Ginkgo biloba extract 761 is a protective factor of cognitive impairment induced by chronic fluorosis.

June 2013 | Biological Trace Element Research | Zhang C, Ren C, Chen H, Geng R, Fan H, Zhao H, Guo K, Geng D. | 153(1-3):229-36.

JNK and NADPH oxidase involved in fluoride-induced oxidative stress in BV-2 microglia cells.

August 29, 2013 | Mediators of Inflammation | Yan L, Liu S, Wang C, Wang F, Song Y, Yan N, Xi S, Liu Z, Sun G. | 2013:895975. doi: 10.1155/2013/895975.

Abstract Excessive fluoride may cause central nervous system (CNS) dysfunction, and oxidative stress is a recognized mode of action of fluoride toxicity. In CNS, activated microglial cells can release more reactive oxygen species (ROS), and NADPH oxidase (NOX) is the major enzyme for the production of extracellular superoxide in microglia. ROS have been characterized as an important secondary messenger and modulator for various mammalian intracellular signaling pathways, including the MAPK path

Relationship between intracellular Ca²+ and ROS during fluoride-induced injury in SH-SY5Y cells.

June 2013 | Environmental Toxicology | Xu Z, Xu B, Xia T, He W, Gao P, Guo L, Wang Z, Niu Q, Wang A. | 28(6):307-12.

Neonatal sevoflurane anesthesia induces long-term memory impairment and decreases hippocampal PSD-95 expression without neuronal loss.

April 2013 | European Review for Medical and Pharmacological Sciences | Wang SQ, Fang F, Xue ZG, Cang J, Zhang XG. | 17(7):941-50.

Effect of selenium on fluoride-induced changes in synaptic plasticity in rat hippocampus.

November 2013 | Biological Trace Element Research | Qian W, Miao K, Li T, Zhang Z. | 155(2):253–260.

The influence of chronic fluorosis on mitochondrial dynamics morphology and distribution in cortical neurons of the rat brain.

March 2013 | Archives of Toxicology | Lou DD, Guan ZZ, Liu YJ, Liu YF, Zhang KL, Pan JG, Pei JJ. | 87(3):449-57.

Toxicity of sodium fluoride to Caenorhabditis elegans.

April 2012 | Biomedical and Environmental Sciences | Li Q, Zhang SH, Yu YH, Wang LP, Guan SW, Li PF. | 25: 216-23.

Low glucose utilization and neurodegenerative changes caused by sodium fluoride exposure in rat’s Developmental Brain.

March 2014 | NeuroMolecular Medicine | Jiang C, Zhang S, Liu H, Guan Z, Zeng Q, Zhang C, Lei R, Xia T, Wang Z, Yang L, Chen Y, Wu X, Zhang X, Cui Y, Yu L, Wang A. | 16(1):94-105.

Protective effect of ascorbic acid and Ginkgo biloba against learning and memory deficits caused by fluoride.

January 2016 | Toxicology and Industrial Health | Jetti R, Cv R, Rao CM. | 32(1):183-7.