Treatment of osteoporosis with sodium fluoride: An appraisal.
1983
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Bone and Mineral Research
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Riggs BL.
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Annual 2: 366-393.
Crippling fluorosis... is characterized by dense bones, exostoses, neurologic complications due to bony overgrowth, osteoarthritis, and ligamentous calcification.
... new bone formed under the stimulus of fluoride administration may exhibit various degrees of osteosclerosis, osteoporosis, osteomalacia, and architectural disorganization. Of these manifestations, only osteosclerosis increases bone strength. When fluoride is used therapeutically, therefore, it is obvious that conditions must be