Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
-

Association between fluoride exposure and kidney function in adults: A cross-sectional study based on endemic fluorosis area in China.

September 16, 2021 | Ecotoxicology and Environmental Safety | Wu L, Fan C, Zhang Z, Zhang X, Lou Q, Guo N, Huang W, Zhang M, Yin F, Guan Z, Yang Y, Gao Y. | 225:112735.
4. Discussion We examined the relationship between urinary fluoride concentrations and levels of markers of kidney function (urinary NAG, serum RBP, serum Urea, serum C3 serum UA and serum ?1-MG) in a cross-sectional study of endemic fluorosis in China. We found that the levels of urinary NAG and serum Urea increased significantly with the increase of urinary fluoride concentration, urinary fluoride was negatively correlated with C3 in adults. Specifically, an increment of 1 mg/L in urinar

Elevated serum fluoride levels in perimenopausal women are related to the components of metabolic syndrome.

September 16, 2021 | European Review for Medical and Pharmacological Sciences | Schneider-Matyka D, Gutowska I, Panczyjk M, Grochans E, Szkup M. | 25:5474-5482.
Excerpt Introduction Metabolic syndrome (MetS) is defined as a cluster of symptoms whose coexistence significantly contributes to cardiovascular disease, type 2 diabetes, stroke, and other conditions, thus increasing the risk of premature death1. The definition of MetS has evolved over time into its current form, adopted in 2009. The components of this disorder include: reduced high-density lipoprotein cholesterol, and increased waist circumference, triglycerides (TG), blood pressure and fasti

Exposure to Fluoride induces apoptosis in liver of ducks by regulating Cyt-C/Caspase 3/9 signaling pathway.

August 16, 2021 | Ecotoxicology and Environmental Safety | Ouyang Z, Yang B, Yi J, Zhu S, Lu S, Liu Y, Li Y, Li Y, Mehmood K, Hussain R, Ijaz M, Guo J, Tang Z, Li Y, Zhang H. | 224:112662.
Highlights Long-term exposure NaF induced hepatotoxicity in ducks. NaF exposure caused liver granule and vacuolar degeneration observed by histological analysis. The mechanism of NaF exposure on hepatotoxicity involving activating autophagy and apoptosis. Cyt-C/Caspase 3/9 signaling pathway activation target cell death. Abstract Fluorine being a well-known and essential element for normal physiological functions of tissues of different organisms is frequ