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Outcome of Systemic Fluoride Effects on Developmental Neurocognitions and Psychopathology in Adolescent Children. (Letter).

To the Editor: The Centers for Disease Control recognized community water fluoridation as one of the 10 great public health achievements of the twentieth century for improving oral health, especially in children [1]. Unfortunately, long-term exposure to higher endemic water fluoride caused dental fluorosis, skeletal fractures, cancers, and affected reproduction, thyroid functions, and intelligence quotient (IQ) [2, 3]. The present study analyzed the outcome of spectral severity of water flu

Effects of Fluorine on Neutrophil Extracellular Trap Formation through Regulating AMPK/p38 Signaling Pathway.

1. Introduction Fluoride is one of the essential microelements in the body. Long-term excessive intake of fluoride will cause systemic physiological and pathological changes [1]. Fluoride can not only damage bone organs but also accumulate in brain tissue through the blood-brain barrier, affecting the shape and function of brain nerve cells [2, 3]. In recent years, fluoride pollution is serious due to the development of industry. Meanwhile, increased fluorine in water will cause a certain toxic