Notes
1.There are current proposals to introduce water fluoridation in a number of areas in England including Southampton, Bristol, parts of Yorkshire and the North West. In Southampton, 72% of those consulted opposed the scheme but the SCSHA still voted to go ahead with the scheme on the basis that they felt health benefits outweighed all other considerations. Recent proposals by the new coalition government about substantial NHS reorganisation and the abolition of SHAs and local PCTs and
Footnotes
Acknowledgements: L. McLaren is supported by a Population Health Investigator Award from Alberta Innovates–Health Solutions. J.C.H. Emery is the Svare Professor in Health Economics at the University of Calgary.
Conflict of Interest: None to declare.
References
1. Rose G. The Strategy of Preventive Medicine. Oxford, UK: Oxford University Press; 1992. [Google Scholar]
2. Hawe P, Potvin L. What is population health intervention research? Can J Public Health.
Abstract
Most riboswitches are metabolite-binding RNA structures located in bacterial messenger RNAs where they control gene expression. We have discovered a riboswitch class in many bacterial and archaeal species whose members are selectively triggered by fluoride but reject other small anions, including chloride. These fluoride riboswitches activate expression of genes that encode putative fluoride transporters, enzymes that are known to be inhibited by fluoride, and additional pr
