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Environmental exposures and pediatric kidney function and disease: A systematic review.

Two studies investigated the association of fluoride exposure, including 1 cross-sectional and 1 case-control. In a cross-sectional study of fluoride exposure in 210 children in China, the investigators found increases of urine NAG and urine ?-GT levels (Liu et al., 2005). In case-control study of fluoride levels in 210 children in China, slightly higher urine NAG levels were found in participants with higher serum fluoride levels (Xiong et al., 2007). While both studies were from China, the f