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Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Fluoride Induced Down-regulation of IKBKG Gene Expression Inhibits Hepatocytes Senescence.

November 4, 2021 | Journal of Trace Elements in Medicine and Biology | Wu CX, Mao CY, Deng J, Zhang T, Zhao Y, Guan ZZ, Hu XX, Qi XL. | [Epub ahead of print]
4. Discussion Cellular senescence is a pathophysiologica l phase in which the cell cycle is arrested and cells stop growing. In recent years, cellular senescence has been widely highlighted as one of the pathogenesis mechanisms that regulate various diseases such as tumors, degenerative diseases, and chronic diseases [20]. The reason and mechanism of cell senescence are not fully understood. Oxidative stress is the main external cause of cell senescence that is more generally accepted. Cells