Effects of Fluorine on Neutrophil Extracellular Trap Formation through Regulating AMPK/p38 Signaling Pathway.
August 3, 2021
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Oxidative Medicine and Cellular Longevity
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Song Y, Zhang Y, Zhang P, Yu P, Shang X, Lu Y, Li Y, Gao H.
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Article ID 6693921
1. Introduction
Fluoride is one of the essential microelements in the body. Long-term excessive intake of fluoride will cause systemic physiological and pathological changes [1]. Fluoride can not only damage bone organs but also accumulate in brain tissue through the blood-brain barrier, affecting the shape and function of brain nerve cells [2, 3]. In recent years, fluoride pollution is serious due to the development of industry. Meanwhile, increased fluorine in water will cause a certain toxic