We appreciate your patience as we fix inconsistencies in the study tracker and research databases.

Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
  • Health Category:
  • Health Sub-Category:

  • Study Type:

  • Publish Date:

    -

Exposure to environmental neurotoxic substances and neurodevelopment in children from Latin America and the Caribbean.

January 2021 | Environmental Research | By José G.Dórea | 192:110199.
Introduction Environmental neurotoxicants are pollutants that can negatively affect many cellular metabolic-processes through different pathways: neuroendocrine/thyroid hormone disruption (Pb, methyl-Hg, organochlorines, and polychlorinated biphenyls-PCB), oxidative stress (Pb, methyl-Hg, organochlorines, and chlorpyrifos), dopamine dysfunction (Pb, methyl-Hg, As, chlorpyrifos, pyrethroids, and organochlorines) (Heyer and Meredith, 2017; Rock and Patisaul, 2018). Pistollato et al. (2020)

Metabolism and Toxicity of Fluorine Compounds

January 29, 2021 | Chemical Research in Toxicology | Kyzer JL, Martens M. | 34:678?680.
Abstract Fluorine has many beneficial features and applications but can cause toxicity at high doses. Herein, we describe its chemical properties and benefits to agrochemical design as well as potential metabolic liabilities and exposure assessment in vivo.   The use of fluorine in drugs and agricultural chemicals has greatly expanded since the first fluoro compound, fludrocortisone, was approved in 1955. In 2018–2019, 45% of small molecule drugs approved by the U.S.

Carious lesions in permanent dentitions are reduced in remote Indigenous Australian children taking part in a non-randomised preventive trial.

January 28, 2021 | PLoS One | Lalloo R, Tadakamadla SK, Kroon J, Jamieson LM, Ware RS, Johnson NW. | 16(1):e0244927
Excerpt Discussion ... While our annual intervention reduced caries incidence, caries increment remains unacceptably high in this community, even in children who received it. These interventions are resource-intensive, so consideration should be given to proven cost-effective interventions such as the reintroduction of water fluoridation. If active interventions are needed, consideration should be given to expanding the roles of community health workers to deliver preventive programs, especial

Serum Concentration of Fluoride in Patients with Alcoholic Liver Cirrhosis from the Lublin Region in Eastern Poland.

January 27, 2021 | International Journal of Environmental Research and Public Health | Prystupa A, Sak J, Kicinski P, Stenzel-Bembenek A, B?azewicz A. | 18(3):1115
Excerpt 4. Discussion ... In our study higher serum fluoride concentrations were associated with changes in liver related parameters. In all Pugh-Child score groups of analyzed patients with different stages of alcoholic liver cirrhosis, elevated levels of plasma fluoride, increased activities of both hepatic aminotransferases, ALT and AST, and total bilirubin concentration were shown. The risk of serious complications like esophageal varices, ascites and encephalopathy was high