Memory impairment induced by chronic sodium fluoride intake.
October 2007
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European Neuropsychopharmacology
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Andreatini R, Chioca LR, Rauppp IM, Da Cunha, Losso EM.
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17(4):S247.
Methods: Male rats received sodium fluoride in their drinking water (1 ppm – tap water; 50 ppm; 100 ppm) for 30 days. After this period, different groups of animals were tested in openfield habituation (two 5-min sessions 24 h apart) and in the twoway active avoidance (two sessions of 30 trials with 10-s of tone – conditioned stimulus – and 5-s of 0.3mA shock delivery – unconditioned stimulus – at final 5 s of CS). Food and water intake, body weight gain and dental fluorosis were also