The value of the hedgehog signal in osteoblasts in fluoride-induced bone-tissue injury.
February 26, 2021
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Journal of Orthopaedic Surgery and Research
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Deng C, Xu L, Zhang Y, Zhao L, Linghu Y, Yu Y.
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16(1):160.
Introduction
Endemic fluorosis is a systemic, chronic, toxic disease characterized by skeletal fluorosis and dental fluorosis, which is caused by the long-term intake of fluorine by residents through drinking water, food, air, and other means that exceeds normal physiological needs. It is one of the most widespread and serious endemic diseases in China [1]. After the implementation of prevention and control measures, such as improvements to the water supply and to stoves, the prevalence