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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses.

May 8, 2020 | Archives of Toxicology | Guth S, Huser S, Roth, A, Degen G, Diel P, Edlund K, Eisenbrand G, Engel KH, Epe B, Grune T, Heinz V, Henle T, Humpf HU, Jager H, Joost HG, Kulling SE, Lampen A, Mally A, Marchan R, Marko D, Muhle E, Nitsche MA, Rohrdanz E, Stadler R, van Thriel C, Vieths S, Vogel RD, Wascher E, Watzl C, Nothlings U, Hengstler JG. | 94:1375–1415

Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses.

May 8, 2020 | Archives of Toxicology | Guth S, Hüser S, Roth A, Degen G, Diel P, Edlund K, Eisenbrand G, Engel KH, Epe B, Grune T, Heinz V, Henle T, Humpf HU, Jäger H, Joost HG, Kulling SE, Lampen A, Mally A, Marchan R, Marko D, Mühle E, Nitsche MA, Röhrdanz E, Stadler R, van Thriel C, Vieths S, Vogel RF, Wascher E, Watzl C, Nöthlings U, Hengstler JG. | 94:1375–1415.

Fluoride and Brain: A Review.

May 1, 2020 | International Journal of Pharmaceutical Sciences and Research | Ghosh S and Ghosh D. | 5: 2011-2017.
ABSTRACT: The mammalian central nervous system is composed of the brain and spinal cord. The brain is protected by the blood-brain barrier (BBB) that allows selective traffic of substances into the brain. Fluoride is a highly toxic and reactive element. We get exposed to fluoride due to its common use in toothpaste, dental gels, non-stick pans, razor blades, etc. Fluoride also enters our food chain through fishes that are cultivated in water bodies, which get contaminated with fluoride from

Protective role of maize purple plant pigment against oxidative stress in fluorosis rat brain.

April 21, 2020 | Translational Neuroscience | Li B, Varkani KN, Sun L, Zhou B, Wang Z, Guo L, Zhang H, Zhang Z. | 11(1):89-95.
Excerpts 1 Introduction Given the widespread presence of fluorine in the natural environment, individuals are exposed to fluoride via food intake, inhalation, and dermal contact. Drinking water represents the largest exposure source. In particular, in highly fluoridated regions and in some developed areas that fluoridate the public water supply to reduce dental caries, fluoride may result in a health hazard [1,2]. Fluoride is required for normal growth and development of teeth and bones but