A Benchmark Dose Analysis for Maternal Pregnancy Urine-Fluoride and IQ in Children.
November 4, 2020
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MedRxiv
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Grandjean P, Hu H, Till C, Green R, Bashash M, Flora D, Tellez-Roj MM, Song P, Lanphear B, Budtz-Jorgensen E.
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[Epub ahead of print]
This article is a preprint and has not been peer-reviewed. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice.
Abstract
As a safe exposure level for fluoride in pregnancy has not been established, we used data from two prospective studies for benchmark dose modeling. We included mother-child pairs from the Early Life Exposures in Mexico to Environmental Toxicants (ELEMENT) cohort in M