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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Taurine reverses sodium fluoride-mediated increase in inflammation, caspase-3 activity, and oxidative damage along the brain-pituitary-gonadal axis in male rats.

June 27, 2017 | Canadian Journal of Physiology and Pharmacology | Adedara IA, Olabiyi BF, Ojuade TD, Idris UF, Onibiyo EM, Farombi EO. | 95(9):1019-1029.
References   Abd El Tawab AM, Shahin NN, AbdelMohsen MM. 2014. Protective effect of Satureja montana extract on cyclophosphamide-induced testicular injury in rats. Chem.-Biol. Interact. 224: 196-205 Crossref, Medline, ISI, Google Scholar.   Adedara IA, Ojuade TJD, Olabiyi BF, Idris UF, Onibiyo EM, Ajeigbe OF, Farombi EO. 2017. Taurine ameliorates renal oxidative damage and thyroid dysfunction in rats chronically exposed to fluoride. Biol. Trace Elem. Res. 175: 388-395 Crossref, Medl

Investigation of the genotoxic effects of fluoride on a bone tissue model .

October 1, 2020 | Toxicological Research | Volobaev VP, Kalyuzhnaya EE, Schetnikova EA, Korotkova AD, Naik AA, Bach SN, Prosekov AY, Larionov AV. | 36:337–342.
References Lav KH, Baylink DJ (1998) Molecular mechanism of action of fluoride on bone cells. J Bone Miner Res 13:1660–1667 Article  Google Scholar Perumal E, Paul V, Govindarajan V, Panneerselvam L (2013) A brief review on experimental fluorosis. Toxicol Lett 223:236–251 CAS  Article  Google Scholar Purohit SD, Gupta RC, Mathur AK, Gupta N, Jeswani ID, Choudhary VK (1999) Experimental pulmonary fluorosis. Indian J Chest Dis Allied Sci 41:27–34 CAS  Pu

Assessment of fluoride levels during pregnancy and its association with early adverse pregnancy outcomes.

June 2020 | Journal of Family Medicine and Primary Care | Goyal LD, Bakshi DK, Arora JK, Manchanda A, Singh P. | 9(6):2693-8
Background and Aim: There is sparse data available on human subjects regarding the affect of excessive fluoride exposures on pregnancy. The aim of this study was to examine the association between elevated urinary fluoride levels during early pregnancy and maternal anemia and adverse fetal outcome. Patients and Methods: We enrolled 600 pregnant patients with gestational age less than 20 weeks and with a high urinary fluoride levels(>1 mg/L).We also documented the fluoride levels in the tap

Conservative esthetic management of severe dental fluorosis with in-office power bleaching.

July-September 2020 | Annals of African Medicine | Ambar W Raut, Vijay Mantri, Priyanka V Gedam, Pooja P Phabyani. | 19(3):211-214.
Abstract Fluorosis is an endemic disease, prevailing in about 25 countries globally. Dental fluorosis is an acquired defect of enamel due to the exposure of an individual to excessive fluoride levels during tooth development. It could result in mild-to-severe discoloration of teeth, which might necessitate esthetic correction. Bleaching is one of the common treatment modalities used in the esthetic correction of such cases. In-office power bleaching is one of the techniques of tooth bleaching t

A randomised oral fluoride retention study comparing intra-oral kinetics of fluoride-containing dentifrices before and after dietary acid exposure.

September 2020 | Archives of Oral Biology | Gary Burnett, Marc Nehme, Charles Parkinson, Ritu Karwal, Thomas Badrock, Gavin Vaughan Thomas, Peter Hall. | 119:104891.
Acknowledgments Editorial assistance with the preparation of manuscript drafts was provided by Juliette Allport, Leading Edge, and Eleanor Roberts, Beeline Science Communications Ltd., both funded by GSK Consumer Healthcare [GlaxoSmithKline] *Read full text online at https://www.sciencedirect.com/science/article/pii/S0003996920302697#!