Excerpts
In an attempt to find the reason why the anaerobic breakdown of glucose in brain is less in poliomyelitis, experiments were performed using sodium fluoride as an inhibitor (Table II). The percentage inhibition resulting from fluoride was consistently higher in the normal than in the infected brain, particularly with lower concentrations of fluoride. The residual glycolysis in poliomyelitic brain treated with fluoride was equal to the glycolysis in normal brain with fluoride in every ex
Extract
Like the skin and its appendages, the teeth, nails and hair, so also other tissues of ectodermal origin are here shown to be affected by fluorine. The action of fluorine consists in lowering the level of the calcium in the blood and tissues. The epithelia of the mouth and the salivary glands, of the nasopharynx, the conjunctivae and the lachrymal glands may be affected. Signs and symptoms are thus produced which are closely similar to those usually attributed primarily to infection. It
Correspondence
FLUORINE AND FLUOROSIS
Sir,
With regard to your remark 'This has led to the suggestion that non-toxic amounts of sodium fluoride. may be added to drinking water for the prevention of dental decay' in the editorial of June number 1944, I wish to draw your attention to the fact that the use of fluorine in dental treatment is in vogue already. A good account was published by Prof. E. H. Lukmsky, Director, Stomatological Clinic, First Moscow State Medical Institute (fluorine cu
Therapeutics and Pharmacy.
CALCIUM FLUORIDE
The therapeutic uses of the fluorides have received comparatively little attention, notwithstanding the fact that it is now generally recognised that a certain amount of fluorine in the form of calcium fluoride is a necessity for the proper strengthening and consistence of the bones and for the normal hardness and good condition of the teeth. According to the Pharmaceutical Journal, however, at least two observers have successfully employed calcium f
Excerpt
BY A. W. MAYO ROBSON, F.R.C.S.,
Honorary Surgeon, Leeds General Infirmary; and Lecturer on Practical Surgery
at the Yorkshire College.
A PERFECT antiseptic for surgical purposes has yet to be found. It must be at the same time a strong germicide, non-poisonous, unirritating to the skin or to the tissues, inodorous, non-volatile, not destroyed by oxidation, non-corrosive to steel instruments, non-injurious to sponges, and inexpensive. In " salufer " (silicofluoride of sodium) we hav
FOR some 8 or 9 years past the presence of fluorine in water supplies has been attracting much attention, chiefly as a danger and as the cause of endemic dental fluorosis, or mottled enamel, which has been reported in some 300 communities in 23 states of the Union.
According to Dean,1 this condition was first described by J. M. Eager 2 in a report from Naples under the name " Denti di Chiaie (Chiaie teeth)," so called from Dr. Stephano Chiaie, who first observed the condition in Italy, where
About the month of April 1936 the district health officer, Nellore, Dr. Lakshminarayana, had his attention drawn by the health inspectors of Podili and Darsi ranges of the Nellore district to a disease characterized by a definite train of symptoms and which was very prevalent in the district. The most obvious symptoms of this disease were stiffness and pain in the spinal region and in various joints. Cattle were stated to be similarly affected. In August 1936, the district health offic
Excerpt
THE endemic hypoplasia of the permanent teeth known in this country as mottled enamel was first reported by Eager in 1901. The first investigation in the United States was the extensive one of Black,2 and McKay,3 published in 1916. At present in this country alone there are more than 200 areas where endemic mottled enamel has been confirmed by survey; in addition there are approximately 100 areas where the endemicity has been reported but not confirmed by survey. These approximate 300 a
