Many years ago I consulted 2 patients suffering from recurrent aphthous ulceration to establish whether they had a toothpaste allergy. I thus proceeded to do many p-tests on the skin but without any positive results. However, replacement of the toothpaste with a simple soap quickly cured the ulcerations. A third case was referred to me with the same symptoms but in this case an unfortunate re-exposure caused a relapse of the ulcerations. At that time, it was unthinkable to speak of any kind of a
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Endemic fluorosis may increase the severity of osteoarthritis in the knees. . . . Twelve patients (21.4%) with endemic fluorosis and eight control patients (20%) had grade 2 osteoarthritis, 16 patients (28.6%) with endemic fluorosis and three control patients (7.5%) had grade 3 osteoarthritis, and six patients (10.7%) with endemic fluorosis and one control patient (2.5%) had grade 4 osteoarthritis. The osteoarthritis severity was greater in the endemic fluorosis group. Osteophytes at the anterio