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Aloe vera protects against fluoride-induced teratogenic effects during pre- and postnatal development in mice.

References Aboubakr M, Elbadawy M, Soliman A, Hewaity M (2014) Embryotoxic and teratogenic effect of norfloxacin in female albino rats. Adv Pharmacol Pharmaceutical Sci 2014:1–6. https://doi.org/10.1155/2014/924706 CAS  Article  Google Scholar Anuradha CD, Kanno S, Hirano S (2001) Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60cells. Free Rad Biol Med 31(3):367–373. https://doi.org/10.1016/s0891-5

Impaired V-ATPase leads to increased lysosomal pH, results in disrupted lysosomal degradation and autophagic flux blockage, contributes to fluoride-induced developmental neurotoxicity.

1. Introduction Fluoride is widespread and unevenly distributed in the environment, and it can be rapidly absorbed into the body via water, food, and air (Johnston and Strobel, 2020). Fluoride consumption at the prescribed level is essential for human health, whereas excessive fluoride exposure is harmful to health. Groundwater, minerals, soil, household chemical products such as varnishes, gels, mouthwashes, and toothpaste are significant sources of fluoride exposure. Others include industrial

Variations in the Sporulation Efficiency of Pathogenic Freshwater Oomycetes in Relation to the Physico-Chemical Properties of Natural Waters.

Furthermore, the PLS-R modelling results suggest that increased fluoride and ammonium concentration could also act as a sporulation trigger, at least for S. parasitica. The range of fluoride concentrations in freshwater is between 0.01 and 0.3 mg/L [57], which is in accordance with the average fluoride concentration of 0.1 mg/L in our dataset. The induction of sporulation by environmentally relevant fluoride concentrations could be explained as a response to unfavorable environmental condition