Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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A roentgenologic study of a human population exposed to high-fluoride domestic water; a ten-year study

November 1955 | American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine | Leone NC, Stevenson CA, Hilbish TF, Sosman MC. | 74(5):874-85.
As shown in Table 1, a limited number of participants from both Bartlett and Cameron showed some degree of roentgenographic bone change but, in general, these changes were minimal. There was a larger number with no observable change in the ten-year interval, a fact disregarded or unreported in most fluoride studies. It was therefore evident that high concentrations of fluoride in drinking water did not uniformly produce bone change of a type detectable in even an appreciable portion of the parti

Review of the Bartlett-Cameron survey: a ten year fluoride study.

March 1955 | Journal of the American Dental Association | Leone NC, Shimkin MB, Arnold FA, Zimmerman ER, Geiser PB, Lieberman JE. | 50(3):277-81.
Analysis of the data produced the following conclusions: 1.  As was expected, dental fluorosis was significantly greater in Bartlett than in Cameron (all of the participants born and in continuous residence in Bartlett during the tooth formative period exhibited positive evidence of dental fluorosis). 2.  The incidence of cardiovascular disease was higher in Cameron, an observation unrelated to fluoride ingestion. 3.  There were no significant differences between the age-adjusted dea

Histological and chemical studies in man on effects of fluoride

June 1965 | Public Health Reports | Call RA, Greenwood DA, Lecheminant WH, Shupe JL, Nielsen HM, Olson LE, Lamborn RE, Mangelson FL, Davis RV. | 80:529-38.
Comparison of fluoride content in the soft tissues of persons meeting the criteria of exposure to fluoride with the content in soft tissues of persons not meeting the criteria  revealed no significant difference (P > 0.05). This finding indicates that fluoride is not stored in the soft tissues in significant quantities (table 3). The fluoride content was higher in the aorta than in any of the other soft tissues studied, a result in agreement with that of Smith and associates. An increase in

Comparison of hydrofluorosilicic acid and pharmaceutical sodium fluoride as fluoridating agents—A cost–benefit analysis

May 2013 | Environmental Science & Policy | Hirzy JW, Carton RJ, Bonanni CD, Montanero CM, Nagle MF. | 38:282-284.
Note from FAN: The authors of this study have issued a "corrigendum" to correct several errors in the above analysis. The corrigendum was published in the April 2014 issue of Environmental Science & Policy (volume 38, pages 282-284). The text of the corrigendum is as follows: In this paper, the first author erroneously used life time exposure data to calculate number of cancer cases while using annual data on cost of fluoridation chemicals to calculate net social costs. Corrections are made