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Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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[RETRACTED] Fluoride Exposure Suppresses Proliferation and Enhances Endoplasmic Reticulum Stress and Apoptosis Pathways in Hepatocytes by Downregulating Sirtuin-1.

August 21, 2022 | BioMed Research International | Yu Y, Li L, Yu W, Guan Z. | 2022:7380324.
1. Introduction Fluorine exists in the environment in the form of fluoride [1]. And fluorine is a vital trace element present in humans and animals, mainly in bones and teeth [2, 3]. While long-term exposure to fluoride in the air, food, and water can lead to fluorosis, it can also cause dental fluorosis and fluorosis bone disease [4]. It has also been confirmed that chronic fluorosis can result in extensive pathological damage to the body [5]. Excessive intake of fluorine will cause morphologi