We appreciate your patience as we fix inconsistencies in the study tracker and research databases.

Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
  • Health Category:
  • Health Sub-Category:

  • Study Type:

  • Publish Date:

    -

Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.

September 17, 2018 | Archives of Toxicology | Zhao Y, Li Y, Wang J, Manthari RK, Wang J. | [Epub ahead of print]
Excerpts: Apoptosis, characterized by nuclear fragmentation, chromatic condensation, and caspase activation, is a major molecular mechanism to eliminate cells (Oropesa-.vila et al. 2017 ). Apoptosis is observed widely in liver diseases (Cui et al. 2018 ; Potz et al. 2016 ). Fluoride, as an exogenous toxicant, has been reported to cause apoptosis in the liver (Khan et al. 2018 ). Song et al. (2015 ) reported that chronic fluoride exposure induced the liver apoptosis through activating the apopto