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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Insights into material and structural basis of bone fragility from diseases associated with fractures: how determinants of the biomechanical properties of bone are compromised by disease.

April 2007 | Endocrine Reviews | Chavassieux P, Seeman E, Delmas PD. | 28(2):151-64.
... Osteomalacia may be drug-induced (fluoride or etidronate) or the result of aluminum exposure in parenteral nutrition or hemodialysis. Clinical features are pain, fissures, and fractures, which may occur after minimal trauma (61) ... B. Abnormal mineral: fluorosis The effects of fluoride on bone tissue depend on the cumulative dose: at very low dose, less than 1.5 mg F/d, fluoride prevents the development of dental caries; at doses of about 23 mg F/d, fluoride was proposed in the treatm