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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Effects of addition of fluorine in diets differing in protein content on urinary fluoride excretion, clinical chemistry and thyroid hormones in calves

October 2013 | Revista Brasileira de Zootecnia | Lohakare J, Pattanaik AK. | 42(10):751-58.
[N]o effect of F on thyroid hormones was noticed in the present study. This was contradictory to the findings of Wheeler & Feel (1983), who reported a significant fall in T3 and T4 levels because of adverse impact of fluorosis on the thyroid glands. It was reported that 250 mg/kg and 400 mg/kg F in diet significantly decrease serum T4 and FT4 levels and increase serum TSH, but no significant differences were observed in serum T3 and FT3 after 50 days of treatment (Zhan et al., 2006). S

X-ray absorption and x-ray fluorescence micro-analyses of mineralized tissue of rats which have ingested fluoridated water

1963 | Acta Pathologica et Microbiologica Scandinavica | Rocket H. | 59(1):32-38.
Bone tissue from rats drinking fluoridated water has been investigated by contact microradiography and x-ray fluorescence technique. At high dosages (1 mg F/day) osteosclerosis is seen within a year; later, resorption cavities occur. At more moderate dosages (0.3 mg F/day) no osteosclerosis is seen but resorption cavities sometimes occur, however. No resorption cavities are seen in the skeleton from rats with a fluorine intake of less than 0.1 mg F/day.