As shown in Table 1, a limited number of participants from both Bartlett and Cameron showed some degree of roentgenographic bone change but, in general, these changes were minimal. There was a larger number with no observable change in the ten-year interval, a fact disregarded or unreported in most fluoride studies. It was therefore evident that high concentrations of fluoride in drinking water did not uniformly produce bone change of a type detectable in even an appreciable portion of the parti
Analysis of the data produced the following conclusions:
1. As was expected, dental fluorosis was significantly greater in Bartlett than in Cameron (all of the participants born and in continuous residence in Bartlett during the tooth formative period exhibited positive evidence of dental fluorosis).
2. The incidence of cardiovascular disease was higher in Cameron, an observation unrelated to fluoride ingestion.
3. There were no significant differences between the age-adjusted dea
Comparison of fluoride content in the soft tissues of persons meeting the criteria of exposure to fluoride with the content in soft tissues of persons not meeting the criteria revealed no significant difference (P > 0.05). This finding indicates that fluoride is not stored in the soft tissues in significant quantities (table 3). The fluoride content was higher in the aorta than in any of the other soft tissues studied, a result in agreement with that of Smith and associates. An increase in
