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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Histological and chemical studies in man on effects of fluoride

June 1965 | Public Health Reports | Call RA, Greenwood DA, Lecheminant WH, Shupe JL, Nielsen HM, Olson LE, Lamborn RE, Mangelson FL, Davis RV. | 80:529-38.
Comparison of fluoride content in the soft tissues of persons meeting the criteria of exposure to fluoride with the content in soft tissues of persons not meeting the criteria  revealed no significant difference (P > 0.05). This finding indicates that fluoride is not stored in the soft tissues in significant quantities (table 3). The fluoride content was higher in the aorta than in any of the other soft tissues studied, a result in agreement with that of Smith and associates. An increase in

Comparison of hydrofluorosilicic acid and pharmaceutical sodium fluoride as fluoridating agents—A cost–benefit analysis

May 2013 | Environmental Science & Policy | Hirzy JW, Carton RJ, Bonanni CD, Montanero CM, Nagle MF. | 38:282-284.
Note from FAN: The authors of this study have issued a "corrigendum" to correct several errors in the above analysis. The corrigendum was published in the April 2014 issue of Environmental Science & Policy (volume 38, pages 282-284). The text of the corrigendum is as follows: In this paper, the first author erroneously used life time exposure data to calculate number of cancer cases while using annual data on cost of fluoridation chemicals to calculate net social costs. Corrections are made

Fate of fluorosilicate drinking water additives

August 2002 | Chemical Reviews | Urbansky ET. | 102(8):2837-54.
V. Conclusions and Unresolved Issues There is considerable debate over the composition and even the existence of some homo- and heteroleptic aquo-, fluoro-, and hydroxo complexes of silicon-(IV), which makes it impossible to predict what species might be found in real potable water supplies that are fluoridated or those that naturally contain fluoride and silicates as background ions. The only agreement seems to be that hexafluorosilicate does not undergo cumulative, consecutive displacements o