Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Fluoride Alters Signaling Pathways Associated with the Initiation of Dentin Mineralization in Enamel Fluorosis Susceptible Mice.

October 28, 2020. | Biological Trace Element Research volume | Kao YH, Igarashi N, Abduweli Uyghurturk D, Li Z, Zhang Y, Ohshima H, MacDougall M, Takano Y, Den Besten P, Nakano Y. | 99:3021–3034.
References 1. Fejerskov O, Larsen MJ, Josephsen K, Thylstrup A (1979) Effect of long-term administration of fluoride on plasma fluoride and calcium in relation to forming enamel and dentin in rats. Scand J Dent Res 87(2):98–104 CAS  PubMed  Google Scholar 2. Vieira A, Hancock R, Dumitriu M, Schwartz M, Limeback H, Grynpas M (2005) How does fluoride affect dentin microhardness and mineralization? J Dent Res 84(10):951–957 CAS  Article  Google Scholar 3. Kierd

The cognitive impairment and risk factors of the older people living in high fluorosis areas: DKK1 need attention.

December 9, 2021 | BMC Public Health | Ren C, Zhang P, Yao XY, Li HH, Chen R, Zhang CY, Geng DQ. | 21:2237.
Study of subjects The fluoride concentration of drinking water was high in the Feng County, Xuzhou City, Jiangsu Province, China, where dental fluorosis was very common. However, there was no data available regarding the cognitive function of the individuals who lived in this area. In this study, a total of 272 subjects from the high fluoride drinking water community (water fluoride concentration > 2 mg/L) of Feng County, Xuzhou City, Jiangsu Province, China, were randomly enrolled in this s

Poisoning by organophosphorus nerve agents and pesticides: An overview of the principle strategies and current progress of mass spectrometry-based procedures for verification.

February 2, 2021 | Journal of Mass Spectrometry and Advances in the Clinical Lab | John H, Thiermann H. | 19:20-31.
Highlights Evidence of poisoning with organophosphorus (OP) nerve agents requires biomedical verification. OP nerve agents undergo common biotransformation pathways producing valuable biomarkers. Internationally accepted methods target remaining poison, hydrolysis products and protein-adducts. Mass spectrometry-based methods provide optimum selectivity and sensitivity for identification. Methods, strategies, current proceedings, quality criteria and real cases of poisoning a