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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Fluoride exposure and blood cell markers of inflammation in children and adolescents in the United States: NHANES, 2013–2016.

October 27, 2022 | Environmental Health | Den Besten P., Wells C R., Uyghurturk D A. | 21, Article number: 102
Background Fluoride is a highly electronegative anion which, when present in saliva or other topical dental products, enhances the precipitation of calcium phosphates on the tooth enamel surface [1]. The observation that naturally fluoridated water was associated with reduced dental decay [2] lead the U.S. Public Health Service (PHS) to recommend that 1 ppm fluoride be added to the drinking water as a public health measure to prevent dental caries. In 2015, these recommendations were r

Private Interests and the Start of Fluoride-Supplemented High-Carbohydrate Nutritional Guidelines.

October 12, 2022 | Nutrients | Hujoel P. | 14(20), 4263
1. Introduction Dental caries is the quintessential disease of civilization, a disease which became prevalent with the start of cereal agriculture and rampant with the start of industrial sugar production [1]. A body of evidence supports the hypothesis that a diet leading to dental caries also leads to chronic non-communicable diseases [2]. Most authoritative organizations aimed to protect public health ignore this evidence and take the view that dental caries is the only adverse side-effect

Effects of neuron autophagy induced by arsenic and fluoride on spatial learning and memory in offspring rats.

September 7, 2022 | Chemosphere | Zhao Q, Pan W, Li J, Yu S, Liu Y, Zhang X, Qu R, Zhang Q, Li B, Yan X, Ren X, Qiu Y | Epub ahead of print
Highlights • Arsenic and/or fluoride exposure can impair spatial learning and memory ability in offspring rats, and low-dose combined exposure produces stronger neurotoxicity than exposure alone. • Arsenic and/or fluoride exposure can disrupt synaptic structure and function, which in turn leads to neurotoxicity. • Arsenic and fluoride exposure have an interactive effect on the expression of autolysosome-related proteins in rat hippocampal neurons, as shown