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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Gestational exposure to fluoride impairs cognition in C57 BL/6 J male offspring mice via the p-Creb1-BDNF-TrkB signaling pathway.

May 25, 2022 | Ecotoxicology and Environmental Safety | Li W, Lu L, Zhu D, Liu J, Shi Y, Zeng H, Yu X, Guo J, Wei B, Cai Y, Sun M. | 239:113682.
References Adkins and Brunst, 2021 E.A. Adkins, K.J. Brunst Impacts of fluoride neurotoxicity and mitochondrial dysfunction on cognition and mental health: a literature review Int. J. Environ. Res. Public Health, 18 (24) (2021), p. 12884, 10.3390/ijerph182412884 View Record in ScopusGoogle Scholar Blaylock, 2004 R.L. Blaylock Excitotoxicity: A possible central mechanism in fluoride neurotoxicity Fluoride, 37 (4) (2004), pp. 301-314 View Record in

NHS general dental practitioner claims in the South West for provision of topical fluoride, fissure sealants, radiographs, fillings and extractions for children born in 2009: an analysis of a five-year period.

May 26, 2022 | British Dental Journal | Brown N, Northover R, Harford S, Power R. | [Epub ahead of print]
References Public Health England. National Dental Epidemiology Programme for England: oral health survey of 5-year-olds 2019. 2020. Available at https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/873492/NDEP_for_England_OH_Survey_5yr_2019_v1.0.pdf (accessed April 2022). Health and Social Care Information Centre. Children's Dental Health Survey 2013. Country specific report: England. 2015. Available at https://files.digital.nhs.uk

Caries Experience and Increment in Children Attending Kindergartens with an Early Childhood Caries Preventive Program Compared to Basic Prophylaxis Measures-A Retrospective Cohort Study.

May 19, 2022 | Journal of Clinical Medicine | Amend S, Hartmann T, Heinzel-Gutenbrunner M, Frankenberger R, Krämer N, Winter J. | 11(10):2864.
5. Perspectives and Conclusions Based on the results, limitations, and strengths of the study, the following perspectives and conclusions can be drawn: The children with low SES and fluoride varnish application showed positive long-term effects regarding the reduction in caries. However, the decline in caries cannot be explained by the fluoride varnish application alone, as it may have been influenced by confounding factors that were not collected in the study. By implementing the inte

Hesperidin Attenuates Oxidative Stress, Inflammation, Apoptosis, and Cardiac Dysfunction in Sodium Fluoride-Induced Cardiotoxicity in Rats.

May 23, 2022 | Cardiovascular Toxicology | Varisli B, Darendelioglu E, Caglayan C, Kandemir FM, Ayna A, Genc A, Kandemir O. | [Epub ahead of print]
Data availability The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request. References Caron, S. (2020). Where does the fluorine come from? A review on the challenges associated with the synthesis of organofluorine compounds. Organic Process Research & Development, 24, 470–480. https://doi.org/10.1021/acs.oprd.0c00030 CAS  Article  Google Scholar James, P., Harding, M