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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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The Dunedin Multidisciplinary Health and Development Study: Oral health findings and their implications.

February 4, 2020 | Journal of the Royal Society of New Zealand | Hong CL, Broadbent JM, Thomson WM, Poulton R. | 50(1):35-46.
Child oral health Early dental research from the Dunedin Study primarily focused upon the prevalence of childhood dental caries and its associated protective and causative factors, including community water fluoridation (which commenced in Dunedin in 1967, well before the Study members were born), self-care, and use of dental services. Over 90% of the Study participants had attended a School Dental Service (SDS) clinic by the age of 5 years, and more than half of those were enrolled with the SD

A Systematic Review and Meta-Analysis of the Relationship Between the Severity of Dental Fluorosis and Fluoride Biomarkers in Endemic Areas.

April 9, 2022 | Biological Trace Element Research | Lavalle-Carrasco J, Vergara-Onofre M, González-González R, Bologna-Molina R, Isiordia-Espinoza MA, Gaona E, Molina-Frechero N. | [Epub ahead of print]
References Wei W, Pang S, Sun D (2019) The pathogenesis of endemic fluorosis: Research progress in the last 5 years. J Cell Mol Med 23:2333–2342. https://doi.org/10.1111/jcmm.14185 CAS  Article  PubMed  PubMed Central  Google Scholar Patil MM, Lakhkar BB, Patil SS (2018) Curse of Fluorosis. Indian J Pediatr 85:375–383. https://doi.org/10.1007/s12098-017-2574-z CAS  Article  PubMed  Google Scholar Kurdi MS (2016) Chronic fluorosis: The disease and its a

Fluoride Status and Cardiometabolic Health: Findings from a Representative Survey among Children and Adolescents.

March 31, 2022 | Nutrients | Ballantyne JA, Coyle G, Sarwar S, Kühn T. | 4(7),1459.
Abstract There is preliminary evidence to suggest a positive association between fluoride exposure and higher blood pressure among children, but population-based biomarker studies are lacking. Thus, data from the 2013/2014 and 2015/2016 cycles of the US-based National Health and Nutrition Examination Survey (NHANES) were analysed to evaluate the association between plasma fluoride concentrations and blood pressure among children and adolescents aged 8 to 19 years. Secondary

Variations in the Sporulation Efficiency of Pathogenic Freshwater Oomycetes in Relation to the Physico-Chemical Properties of Natural Waters.

February 27, 2022 | Microorganisms | Pavic D, Grbin D, Gregov M, Curko J, Vladušic T, Šver L, Miljanovic A, Bielen A. | 10(3):520.
Furthermore, the PLS-R modelling results suggest that increased fluoride and ammonium concentration could also act as a sporulation trigger, at least for S. parasitica. The range of fluoride concentrations in freshwater is between 0.01 and 0.3 mg/L [57], which is in accordance with the average fluoride concentration of 0.1 mg/L in our dataset. The induction of sporulation by environmentally relevant fluoride concentrations could be explained as a response to unfavorable environmental condition

ESPEN micronutrient guideline

February 25, 2022 | Clinical Nutrition | Berger MM, Shenkin A, Amrein K, Augsburger M, Biesalski HK, Bischoff SC, Casaer MP, Gundogan K, Lepp HL, de Man AME, Muscogiuri G, Pietka M, Pironi L, Rezzi S, Schweinlin A, Cuerda C. |
6. Fluoride 6.1. Main functions Fluoride is the world's 13th most abundant element [151], being widely distributed in the environment, occurring in soils, rocks, and water: it is therefore naturally present in the food and drink we but its status as “essential” is debated. It is well absorbed by the small intestine. and gets attached to bone and teeth, transforming apatite into fluoroapatite. Nearly 99% of the body's fluoride is bound strongly to calcified tissues. Fluoride in bone appe