Abstract
Skeletal fluorosis is a long-term bone disease that develops when prolonged fluoride toxicity leads to osteosclerosis and bone deformities that result in crippling pain and debility. The disease is endemic to many countries due to environmental or industrial exposures. However, rare cases in the United States have been reported from various causes including heavy toothpaste ingestion, excessive tea consumption, voriconazole us
Funders who supported this work.
National Institute of Dental and Craniofacial Research (1)
U.S. Department of Health and Human Services, NIH National Center for Research Resources (1)
Articles referenced by this article (10)
The prevalence of dental fear and avoidance: expanded adult and recent adolescent surveys.
Gatchel RJ. J Am Dent Assoc, (5):591-593 1989. MED: 2785546
Evaluation of bias and logistics in a survey of adults at increased risk for oral health de
References
1. Enoch DA, Yang H, Aliyu SH, Micallef C. the changing epidemiology of invasive fungal infections. Methods Mol Biol. 2017;1508:17–65. - PubMed
2. Shi C, Xiao Y, Mao Y, Wu J, Lin N. Voriconazole: a review of population pharmacokinetic analyses. Clin Pharmacokinet. 2019;58:687–703. - PubMed
3. Theuretzbacher U, Ihle F, Derendorf H. Pharmacokinetic/pharmacodynamic profile of voriconazole. Clin Pharmacokinet. 2006;45:649–63. - PubMed
4. Benitez LL, Carver PL
