Characteristics of the development of iodine-deficient states in children growing up in conditions of contamination of the surrounding environment with fluoride compounds.
It is known that in the presence of insufficient function of the thyroid gland a whole spectrum of pathologic conditions develops known at the present time as “iodine-deficiency diseases.” The most prevalent manifestations of these diseases include goiter, hypothyroidism, disturbances of physical growth, and intellect
Funding
NIDCR NIH HHS (1)
Fluoride uptake in hard tissues of fetal guinea pigs in response to various dose regimens.
Bawden JW, Deaton TG, Koch GG, Crawford BP
Arch Oral Biol, (11):929-933 1992
MED: 1466641
Review on fluoride, with special emphasis on calcium fluoride mechanisms in caries prevention.
ten Cate JM
Eur J Oral Sci, (5 Pt 2):461-465 1997
MED: 9395110
Title not supplied
AUTHOR UNKNOWN
A review of clinica
Enamel hypoplasia
The pathogenesis of this is that severe metabolic upset causes a permanent mark, called enamel hypoplasia, in the developing tooth which remains as a visible defect on the tooth throughout the life of the patient. The position and extent of the defect indicates the timing, duration and to some extent the severity of the underlying metabolic upset. Enamel hypoplasia is frequently seen in patients with renal disease, and has been attributed to the production of poorly-fo
